REFRESH OPTIVE MEGA-3® Lubricant Eye Drops
Give your dry, burning, or irritated eyes REFRESH OPTIVE MEGA-3® Lubricant Eye Drops—a preservative-free formula that provides fast-acting, lasting relief. These artificial tears deliver advanced hydration that nourishes the eye’s surface and helps protect your natural tears from evaporating.
Specially crafted with natural plant-based oils, antioxidants (inactive ingredients), and moisture-locking technology, this triple-action formula works to soothe symptoms and prevent further irritation.
Safe to use as often as needed. Just apply 1 to 2 drops in the affected eye(s).
Depending on your plan, REFRESH OPTIVE MEGA-3 may be FSA or HSA eligible for you.
Trust your dry eyes to REFRESH—the #1 doctor recommended artificial tears and preservative-free leader with more than 35 years of experience.1
1. Data on file, AbbVie, Inc. REF-113774.
60 Single-Use Vials, 0.4 mL
Product Specifications
- FAST ACTING: Rapid relief to comfort dry, irritated eyes
- LASTING RELIEF: Soothes and prevents further irritation
- TRIPLE-ACTION FORMULA: Lubricates, hydrates, and protects tears from evaporating
- PRESERVATIVE-FREE: Enhanced with antioxidants and plant-based flaxseed oil (inactive ingredients) which contains omega-3s
- ADVANCED HYDRATION: Patented HydroCell® technology hydrates by balancing osmolarity
- ON-THE-GO VIALS: 60 sterile single-use vials per carton that are easy and safe to use as often as needed
- FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense, depending on your plan
- RELIABLE PROTECTION: Active ingredients provide lasting lubrication for dry eyes
For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.
Instill 1 or 2 drops in the affected eye(s) as needed.
Active Ingredients:
- Carboxymethylcellulose sodium 0.5% Eye lubricant
- Glycerin 0.9% Eye lubricant
- Polysorbate 80 0.5% Eye lubricant
Inactive Ingredients:
- Boric acid
- Butylated hydroxyl toluene
- Castor oil
- Erythritol
- Flaxseed oil
- Levocarnitine
- Pemulen TR-2
- Polyoxyl 40 stearate
- Purified water
- Sodium hydroxide
- And trehalose
Warnings: For external use only. To avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard. Do not touch unit-dose tip to eye. If solution changes color, do not use. Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Other Information: Use only if single-use container is intact. Use before expiration date marked on container. Store vials in the pouch until use.
Storage Temperature: 59°-77°F (15°-25°C)
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.
Why Choose REFRESH OPTIVE MEGA-3® Lubricant Eye Drops
- Recommended for Sensitive Eyes
- #1 Selling Preservative-Free Brand
- Hydrocell Technology
- Fast Acting Relief
- Instantly Moisturizes
- Triple-Action
- FSA and HSA Eligible
- Prevents Further Irritation
- Locks In Hydration
- Protects Tears From Evaporating
- Safe to Use as Often as Needed
- Advanced Hydration
- Enriched With Antioxidants*. *Inactive Ingredients
- Features Plant Based Flaxseed Oil*. *Inactive Ingredient
Key Benefits & Uses

Prevents Further Irritation
Keeps eyes feeling better longer.

HydroCell® Technology
HydroCell® technology delivers soothing hydration to the eye’s surface cells.

Enhanced with Flaxseed Oil
Infused with omega-3 fatty acids*, it helps nourish and protect your tear film, promoting overall eye health
*Inactive ingredient

For Dry, Sensitive Eyes
Our innovative, preservative-free formulas.

Use Anytime
Safe for Everyday Use
REFRESH® products are safe to use as often as needed, so you can add them to your daily routine, or reach for REFRESH® when dry eye symptoms arise.

TRUST YOUR EYES TO REFRESH®
Doctor Recommended
Trust your eyes to REFRESH®, the #1 doctor recommended brand, with over 35 years of experience.*
*Data on file, AbbVie, Inc. REF113774.