REFRESH OPTIVE® ADVANCED Preservative Free
REFRESH OPTIVE® ADVANCED Preservative Free Lubricant Eye Drops are a preservative-free, triple-action formula that lubricates and hydrates dry, burning, irritated eyes and helps prevent tears from evaporating. It also features HydroCell® technology, our proprietary NaCl-free, glycerin-based solution that enables hydration and maintains the volume of cells on the eye's surface. The result? Triple-action relief of dry, sensitive eyes.
Safe to use as often as needed, you can add it to your morning or night routine to prevent further irritation.
REFRESH OPTIVE ADVANCED Preservative Free Lubricant Eye Drops come in sterile, single-use vials you can take with you anywhere.
Trust your dry eyes to REFRESH—#1 doctor recommended artificial tears and preservative-free leader with more than 35 years of experience.1
1. Data on file, AbbVie, Inc. REF-113774.
30 Single-Use Vials, 0.4 mL
Product Specifications
- TRIPLE-ACTION RELIEF: Preservative-free drops, great for dry, sensitive eyes
- FAST ACTING: Lubricates and hydrates dry, burning, irritated eyes
- INNOVATIVE FORMULA: Helps prevent tears from evaporating
- ADVANCED HYDRATION: Patented HydroCell® technology hydrates by balancing osmolarity
- RELIABLE PROTECTION: Active ingredients provide lasting lubrication for dry eyes
- ON-THE-GO: Single-use vials
- FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense, depending on your plan
- GENTLE: Safe to use as often as needed
For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.
To open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container.
Active Ingredients:
- Carboxymethylcellulose sodium 0.5% Eye lubricant
- Glycerin 1% Eye lubricant
- Polysorbate 80 0.5% Eye lubricant
Inactive Ingredients:
- Boric acid
- Carbomer copolymer type A
- Castor oil
- Erythritol
- Levocarnitine
- Purified water
- And sodium hydroxide
Warnings: For external use only. To avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard. Do not touch unit-dose tip to eye. If solution changes color, do not use. Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Other Information: Use only if single-use container is intact. Use before expiration date marked on container.
Storage Temperature: 59°-86°F (15°-30°C)
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.
Why Choose REFRESH OPTIVE® ADVANCED Preservative Free
- Recommended for Sensitive Eyes
- #1 Selling Preservative-Free Brand
- Hydrocell Technology
- Fast Acting Relief
- Triple-Action
- FSA and HSA Eligible
- Prevents Further Irritation
- Locks In Hydration
- Protects Tears From Evaporating
- Safe to Use as Often as Needed
- Advanced Hydration
Key Benefits & Uses

Relieves Dry, Burning, Irritated Eyes
Lubricates, hydrates and moisturizes to relieve dry eye symptoms.

Preservative-Free
Ideal for dry, sensitive eyes.

Triple-Action Formula
Hydrates and supports all three tear film layers.

HydroCell® Technology
HydroCell® technology delivers soothing hydration to the eye’s surface cells.

Use Anytime
Safe for Everyday Use
REFRESH® products are safe to use as often as needed, so you can add them to your daily routine, or reach for REFRESH® when dry eye symptoms arise.

TRUST YOUR EYES TO REFRESH®
Doctor Recommended
Trust your eyes to REFRESH®, the #1 doctor recommended brand, with over 35 years of experience.*
*Data on file, AbbVie, Inc. REF113774.